1997;124(4):315-7. No reaction was seen with Zovirax ® ophthalmic ointment and Zovirax ® tablet. It is due to a type IV hypersensitivity reaction following contact with an allergen. Francalanci S, Sertoli A, Giorgini S, et al. OK, So Contact Dermatitis Can Strike The Lips, Too? It is due to a type IV hypersensitivity reaction following contact with an allergen. A 29-year-old Turkish woman with allergic contact cheilitis from a lipstick was misdiagnosed as herpes labialis and subsequently worsened with the application of Zovirax cream. It is due to a type IV hypersensitivity reaction following contact with an allergen. and you may need to create a new Wiley Online Library account. Granulomatous cheilitis is a condition that causes persistent swelling of the lips. USA.gov. 1995 Oct;33(4):255-7. doi: 10.1111/j.1600-0536.1995.tb00477.x. Allergic contact cheilitis generally presents as eczema-like changes on the vermilion margin or skin around the mouth. Allergic contact cheilitis is more common in women than men. 2009 Jul;27(3):265-80, vi. Allergic contact cheilitis is a contact allergic reaction on lips. Irritants include spices, artificial flavors, harsh soaps, toothpaste, moisturizers, lip balms, A 29‐year‐old Turkish woman with allergic contact cheilitis from a lipstick was misdiagnosed as herpes labialis and subsequently worsened with the application of Zovirax ® cream. This may be due to skin diseases such as atopic dermatitis or by contact with allergic or irritant materials, or both. No reaction was seen with Zovirax® ophthalmic ointment and Zovirax® tablet. When contact dermatitis affects the lips, it's referred to as contact cheilitis. A possible cause of cheilitis is contact allergy. Use the link below to share a full-text version of this article with your friends and colleagues. It is due to a type IV hypersensitivity reaction following contact with an allergen and usually presents as an eczema -like inflammation of the outer lip or vermilion margin. In the case of women, lip cosmetics ar… A 29-year-old Turkish woman with allergic contact cheilitis from a lipstick was misdiagnosed as herpes labialis and subsequently worsened with the application of Zovirax cream. Concentration and vehicle adapted for for patch tests]. [Contact eczema induced by propylene glycol. Allergic contact cheilitis is a common cause inflammation of the outer lip or vermillion margin. Lip cosmetics, sunscreens, toothpas… Please enable it to take advantage of the complete set of features! The full text of this article hosted at iucr.org is unavailable due to technical difficulties. Get the latest public health information from CDC: https://www.coronavirus.gov, Get the latest research information from NIH: https://www.nih.gov/coronavirus, Find NCBI SARS-CoV-2 literature, sequence, and clinical content: https://www.ncbi.nlm.nih.gov/sars-cov-2/. Similar to contact dermatitis are irritant cheilitis and allergic cheilitis. Sometimes the reaction extends onto adjacent perioral skin, with or without the involvement of the angles of the mouth. We reviewed its allergic causes, and suspect that the literature does not adequately document the … Allergic contact cheilitis is more common in women than men. Contact Dermatitis. Eczematous cheilitis (also known as contact cheilitis) is dryness, erythema, and/or fissuring of the lips secondary to an inflammatory response to allergens in contact with the lips. The differential diagnosis was challenging due to concomitant contact sensitization with these agents. The propylene glycol component of the Zovirax cream and the propyl gallate component of the lipstick were regarded as the responsible contact sensitizers. One or both lips may be red with dryness, scaling and cracking. Enter your email address below and we will send you your username, If the address matches an existing account you will receive an email with instructions to retrieve your username, I have read and accept the Wiley Online Library Terms and Conditions of Use, https://doi.org/10.1111/j.1440-0960.2007.00380.x. Allergic contact cheilitis describes a not uncommon inflammatory reaction of the lips. Allergic contact dermatitis to Zovirax cream. It's more common in women, probably because they are much more likely to wear lipstick, one of the most frequent causes of contact cheilitis. Adolescent Lip dryness due to internal diseases is less common. doi: 10.1016/j.det.2009.05.014. No evidence of contact sensitization to acyclovir in acute dermatitis of the lips following local application of Zovirax cream.  |  Allergic contact cheilitis caused by carnauba wax in a lip balm. This site needs JavaScript to work properly. Multicentre study of allergic contact cheilitis from toothpastes. COVID-19 is an emerging, rapidly evolving situation. 2013 Nov;69(5):318-9. doi: 10.1111/cod.12108. Allergic contact cheilitis. You bet! Learn about our remote access options, Department of Dermatology, Istanbul Medical Faculty, Istanbul University, Istanbul, Turkey. Lipsticks and other lip care products are the major causes of allergic contact cheilitis of the vermilion margin, where the skin and red lip meet. Sometimes, having itchy lips is a symptom of other less common health conditions. 2008 Mar;58(3):178-9. doi: 10.1111/j.1600-0536.2007.01225.x. Most of the time, having itchy lips is related to a contact or seasonal allergy. Zeynep Topkarcı, MD.  |  Allergic contact cheilitis caused by carnauba wax in a lip balm Contact Dermatitis. Ann Dermatol Venereol. Ophaswongse S, Maibach HI. Patch tests were positive to Zovirax ® cream, propylene glycol, the patient's favourite lipstick and propyl gallate. Exogenous eczematous cheilitis is caused by factors outside the body. The lips may also itch or burn. PMID: 29039219 [Indexed for MEDLINE] Publication Types: Case Reports; MeSH terms. Contact Cheilitis is caused by exposure to irritating chemicals, which can be found in food and skin care products. No reaction was seen with Zovirax ophthalmic ointment and Zovirax tablet. Dermatol Clin. Allergic contact cheilitis is more common in women than men. The reaction may present in either acute or more persistent chronic forms. Eczematous cheilitis is the most common cause. Keep reading to find out what could be causing your lips to feel itchy. Authors Fuad Alrowaishdi 1 , Sophie Colomb, Bernard Guillot, Nadia Raison-Peyron. If you do not receive an email within 10 minutes, your email address may not be registered, Allergic contact dermatitis of the lips, also known as allergic contact cheilitis It doesn't matter whether it's your face, your arms, or your lips. Patch tests were positive to Zovirax cream, propylene glycol, the patient's favourite lipstick and propyl gallate. This can be further broken down into irritant contact cheilitis – which is often caused by lip licking, cosmetics, foods and environmental factors – and allergic contact cheilitis. Allergic contact cheilitis: A relevant allergic reaction is identified in one quarter, at least, of cases of lip eczema. (Cheilitis is the medical word for “inflamed lips” and covers a broad range of causes and symptoms.) Allergic contact cheilitis describes a not uncommon inflammatory reaction of the lips. An itchy sensation on your lips can happen suddenly and be quite uncomfortable. NLM The propylene glycol component of the Zovirax® cream and the propyl gallate component of the lipstick were regarded as the responsible contact sensitizers. The latter can be due to lip products, toothpaste, dental materials, medication or a combination of factors. CONTACT CHEILITIS is an inflammatory condition of the lips that can manifest as itching, burning, dryness, erythema, fissuring, crusting, and edema. Allergic contact cheilitis is allergic contact dermatitis affecting the lip (s). Irritant cheilitis often comes from lip licking, a constant source of irritation to the skin of the lips, and a … Author information: (1)1 Faculty of Medicine, University of Ottawa, Ottawa, ON, Canada. 20-22 Clinically, there is usually a hyperpigmented circumferential symmetric plaque that is … A 29‐year‐old Turkish woman with allergic contact cheilitis from a lipstick was misdiagnosed as herpes labialis and subsequently worsened with the application of Zovirax® cream. The differential diagnosis was challenging due to concomitant contact sensitization with these agents. Please check your email for instructions on resetting your password. A lipstick allergy can be difficult to diagnose in some cases as it is possible that cheilitis can develop without the person even wearing lipstick. Contact cheilitis is a term used to describe inflammation of the lips, most often caused by either irritant contact cheilitis (ICC) or allergic contact cheilitis (ACC) (9). Whenever your skin barrier is impaired, you are at higher risk for allergic skin reactions. Allergic contact cheilitis caused by ditrimethylolpropane triethylhexanoate in a lipstick Allergic contact cheilitis caused by ditrimethylolpropane triethylhexanoate in a lipstick Miura, Maiko; Isami, Mamiko; Yagami, Akiko; Matsunaga, Kayoko 2011-05-01 00:00:00 Lipsticks are composed of dyes, flavouring agents, sunscreens, vehicle components, and preservatives. There are many common sources of allergens including lipsticks and other lip-care products, toothpastes and dental materials, foods, medications and nail varnish. Working off-campus? Contact Dermatitis 1995; 33:365. Chronic sun exposure, such as occurs among people who work outdoors, can lead to inflammatory changes of the lower lip known as actinic or solar cheilitis, reports the New Zealand Dermatological Society on DermNet NZ 4. Clipboard, Search History, and several other advanced features are temporarily unavailable. For some people, soap of any kind may be too harsh for the face and lips. Allergic contact cheilitis is an allergic reaction to lip products, dental materials, toothpaste, or medication. National Center for Biotechnology Information, Unable to load your collection due to an error, Unable to load your delegates due to an error. Learn more. 19 Perioral Region “Lip licker dermatitis” is an irritant dermatitis that involves the perioral skin. Allergic contact cheilitis is a common cause inflammation of the outer lip or vermillion margin. Drugs, lipsticks, sunblock and toothpaste are the most common implicated allergens. Unlimited viewing of the article/chapter PDF and any associated supplements and figures. Allergic contact dermatitis and lip rashes may be due to flavorings in chapsticks, lip balms, toothpaste and food, preservatives in makeup, and other substances. Lip cosmetics are the most common allergen source in women, while toothpastes allergy occur mostly in men. 1996 Oct;51(10):755-6. doi: 10.1111/j.1398-9995.1996.tb02122.x. Allergic contact cheilitis affects more women than men and more adults than children, although it can affect all age groups. Pastor N, Silvestre JF, Mataix J, Lucas A, Pérez M. Contact Dermatitis. Bourezane Y, Girardin P, Aubin F, Vigan M, Adessi B, Humbert P, Laurent R. Allergy. Güzin Özarmağan, MD. Would you like email updates of new search results? Allergic Contact Cheilitis Due to Lip Cosmetics Lipsticks and lipcare products are the commonest cause of allergic contact cheilitis in women. In this case, it was caused by chemical substances contained in the lipstick worn by the patient. Contact Dermatitis 2000; 43:216. Allergic Contact Cheilitis: A delayed-type hypersensitivity reaction to allergens that come in contact with the lips can cause inflammation of the lips. Patch tests were positive to Zovirax® cream, propylene glycol, the patient's favourite lipstick and propyl gallate. HHS View the article PDF and any associated supplements and figures for a period of 48 hours. Causes of cheilitis (2)2 Division of Dermatology, University of Ottawa, Ottawa, ON, Canada. Involvement of the angles of the mouth may also be seen (angular-cheilitis). Allergic contact cheilitis is a chronic superficial inflammatory disorder of the vermilion borders characterized by desquamation due to delayed-type hypersensitivity reaction. Drugs, lipsticks, sunblock and toothpaste are the most common implicated allergens. Allergic or irritant contact cheilitis is caused by a reaction to an irritant or allergen that touches the lips, such as: 2  Lipstick or lip balms Oral hygiene products, like toothpaste or mouthwash Fragrances (e.g., balsam of peru) 3  Granulomatous cheilitis. It is also known as lipstick cheilitis since several ingredients found in lipsticks may act as irritants. Actinic cheilitis is a precancerous condition, which may lead to squamous cell carcinoma if left untreated. Lip cosmetics are the most common allergen source in women, while toothpastes allergy occur mostly in men. Patch tests were positive to Zovirax cream, propylene glycol, the patient's favourite lipstick and propyl gallate. Unlimited viewing of the article PDF and any associated supplements and figures. Contact cheilitis from bisabolol and polyvinylpyrrolidone/hexadecene copolymer in lipstick. Zhou LL(1), Pratt M(2). Allergic Contact Cheilitis From a Variety of Lip Balm Ingredients. Your skin barrier works great in most cases. A possible cause of cheilitis is contact allergy. More than lipstick alone can lead to contact cheilitis, though. Allergic contact cheilitis is the term for itchy or inflamed lips caused by exposure to an allergen. The changes may be fairly localised or affect the whole lip. And as the majority of patients providing with cheilitis are women, this makes these products the most common general source of allergens. Lip cosmetics are the most common allergen source in women, while toothpastes allergy occur mostly in men. If you have previously obtained access with your personal account, please log in. Schena D, Fantuzzi F, Girolomoni G. Contact allergy in chronic eczematous lip dermatitis. Allergic contact cheilitis is a common cause inflammation of the outer lip or vermillion margin. Vaseline may help. It looks like an eczema-type inflammation on the outer edge of the lips and is due to a type IV hypersensitivity reaction following contact with an allergen. Allergic Contact Cheilitis From a Variety of Lip Balm Ingredients Linghong Linda Zhou and Melanie Pratt Journal of Cutaneous Medicine and Surgery 2017 22 : 3 , 333-335 The prototypical vignette is a wife with allergic contact cheilitis driven by an allergy to her husband’s aftershave. Inflammation of the lips is called cheilitis and can be caused by irritation or allergic reactions. The most common causes of allergic contact cheilitis is lip cosmetics, including lipsticks and lip balm, followed by toothpastes.  |  NIH Lip Allergy (Allergic Contact Cheilitis) Allergic contact cheilitis is a form of allergic contact dermatitis that affects the lips. In both situations, you may have rashes elsewhere on your body. Esen Özkaya, MD.